Barangay Santa Isabel

Barangay Santa Isabel forms part of City of San Pablo, a city in Laguna, and is classified as a mid-sized barangay.

According to the 2020 Philippine census, Barangay Santa Isabel had a population of 3,830. This made it the 27th largest of 80 barangays in City of San Pablo by population, placing it in the middle tier of the city. Residents of Barangay Santa Isabel accounted for approximately 1.34% of the total population of City of San Pablo, which stood at 285,348 in the same census year.

Between the 2015 and 2020 censuses, the population of Barangay Santa Isabel changed from 3,503 to 3,830, a shift of +9.3% over the five-year period. This places the barangay among those with growing populations in City of San Pablo. Barangay Santa Isabel is officially classified as rural, a designation applied to barangays with lower population density and predominantly non-built-up land use.

City of San Pablo is a city comprising 80 barangays, and serves as the governing unit directly responsible for local services in Barangay Santa Isabel, including public health, sanitation, peace and order, and civil registration. Within the wider province of Laguna, which contains 681 barangays across its component cities and municipalities, Barangay Santa Isabel ranks 228th by 2020 population. Laguna is classified as a 1st by the Bureau of Local Government Finance, a category that reflects the province's annual regular income.

The barangay's legislative and executive affairs are handled by a Punong Barangay and the Sangguniang Barangay, elected nationwide during the Barangay and SK Elections. The next BSKE is scheduled for Monday, November 2, 2026, following the synchronized election schedule set by COMELEC Resolution No. 11191.