Barangay Santa Cruz

Situated in City of Antipolo, Rizal, Barangay Santa Cruz is one of 16 barangays that make up the city within CALABARZON.

According to the 2020 Philippine census, Barangay Santa Cruz had a population of 65,327. This made it the 7th largest of 16 barangays in City of Antipolo by population, placing it in the middle tier of the city. Residents of Barangay Santa Cruz accounted for approximately 7.36% of the total population of City of Antipolo, which stood at 887,399 in the same census year.

The barangay recorded 62,992 residents in the 2015 intercensal count and 65,327 residents in the 2020 Census — a net change of +3.7%, consistent with a growing settlement. Barangay Santa Cruz is officially classified as urban, reflecting the density and built-up character of the area.

City of Antipolo is a city comprising 16 barangays, and serves as the governing unit directly responsible for local services in Barangay Santa Cruz, including public health, sanitation, peace and order, and civil registration. Within the wider province of Rizal, which contains 189 barangays across its component cities and municipalities, Barangay Santa Cruz ranks 15th by 2020 population. Rizal is classified as a 1st by the Bureau of Local Government Finance, a category that reflects the province's annual regular income.

The barangay's legislative and executive affairs are handled by a Punong Barangay and the Sangguniang Barangay, elected nationwide during the Barangay and SK Elections. The next BSKE is scheduled for Monday, November 2, 2026, following the synchronized election schedule set by COMELEC Resolution No. 11191.