Barangay Santa Cruz

Classified as a small barangay, Barangay Santa Cruz is one of the administrative divisions of San Antonio in Nueva Ecija, Central Luzon, Philippines.

According to the 2020 Philippine census, Barangay Santa Cruz had a population of 1,782. This made it the 15th largest of 16 barangays in San Antonio by population, placing it among the smaller barangays of the municipality. Residents of Barangay Santa Cruz accounted for approximately 2.15% of the total population of San Antonio, which stood at 83,060 in the same census year.

Census comparisons between 2015 and 2020 show Barangay Santa Cruz moving from 1,521 residents to 1,782 residents, an intercensal change of +17.2%. The trajectory indicates a growing community. Barangay Santa Cruz is officially classified as rural, a designation applied to barangays with lower population density and predominantly non-built-up land use.

San Antonio is a municipality comprising 16 barangays, and serves as the governing unit directly responsible for local services in Barangay Santa Cruz, including public health, sanitation, peace and order, and civil registration. Within the wider province of Nueva Ecija, which contains 849 barangays across its component cities and municipalities, Barangay Santa Cruz ranks 502nd by 2020 population. Nueva Ecija is classified as a 1st by the Bureau of Local Government Finance, a category that reflects the province's annual regular income.

The barangay's legislative and executive affairs are handled by a Punong Barangay and the Sangguniang Barangay, elected nationwide during the Barangay and SK Elections. The next BSKE is scheduled for Monday, November 2, 2026, following the synchronized election schedule set by COMELEC Resolution No. 11191.